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-- Florida Gov. Charlie Crist announces decision to quit the GOP's Senate primary race and run without party affiliation.

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-- White House declares Gulf of Mexico oil spill to be of "national significance," freeing up aid.

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-- AstraZeneca fined $520 million for illegally marketing antipsychotic drug Seroquel, Justice Department says.

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-- U.S. official: Panama ex-dictator Noriega sent to France from U.S. prison. France wanted him on drug-related charges.

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-- National Weather Service: Large tornado kills at least two people in Mississippi. Rescue operations are ongoing.

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-- Arizona governor signs immigration law that is considered to be among the toughest in the United States.

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-- Seven people -- including six police officers -- were killed in a shootout in Ciudad Juarez, Mexico, the mayor says.

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-- Utah judge signs death warrant allowing state to execute Ronnie Lee Gardner using firing squad, court official says.

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-- Oil rig burning in Gulf of Mexico sinks, U.S. Coast Guard tells CNN.

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-- At least 11 people are missing, seven critically injured after oil rig explodes in Gulf of Mexico, U.S. Coast Guard says.

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-- British officials: UK airspace to reopen at 10 p.m. (5 p.m. ET) after nearly a week of closure due to ash from a volcano.

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-- 14 alleged members of Gambino mob family arrested and charged with murder, jury tampering, other crimes, feds say.

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-- Keli McGregor, president of Colorado Rockies baseball team, found dead in a Salt Lake City hotel today, police say.

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-- U.S. official: Toyota has indicated it will pay a $16.4 million fine for failing to promptly give notice of a defect.

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-- EU official: Test flights show no impact in European air space from volcanic ash that has disrupted air travel this week.

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-- SEC charges Goldman Sachs with defrauding investors about products tied to subprime mortgages.

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-- President Obama tells agency to establish rule barring hospitals from denying visitation to gay, lesbian partners.

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-- Mazda recalls nearly 90,000 vehicles because of transmission problems, a company spokesman says.

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-- About 300 dead, 8,000 injured in China quake, Xinhua news agency reports.

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-- Toyota asks dealers to temporarily halt sales of 2010 Lexus GX 460 SUV after a Consumer Reports safety warning.

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-- President Obama says nations at summit endorse goal to secure all vulnerable nuclear materials within four years.

Watch live coverage now on http://CNN.com/Live

>+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=
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-- First lady Michelle Obama makes unannounced visit to Haiti.

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-- All bodies have been removed from a West Virginia mine, says the state Office of Miners' Health, Safety and Training.

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-- NFL's Ben Roethlisberger won't face criminal charges after sex assault allegation, Georgia district attorney says.

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-- Conan O'Brien will host a new late-night talk show on TBS, the cable TV network says.

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-- Phil Mickelson has won his third green jacket with a final-round 67 to win by three shots over Lee Westwood.

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-- Eight people killed in clashes between anti-government protesters and Thai police and military, emergency center says.

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-- Polish president Lech Kaczynski feared dead after plane crash at western Russia airport.

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-- West Virginia governor says four missing miners have been found dead.

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-- Supreme Court Justice John Paul Stevens plans to retire, the high court's press office reports.

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-- Rep. Bart Stupak, D-Michigan, will reveal Friday he is retiring from Congress, Democratic sources tell CNN.

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-- The United States and Russia have signed a comprehensive nuclear arms treaty.

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-- Rescue teams to re-enter West Virginia mine to search for missing miners after air quality deemed safe.

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-- Passenger on a United flight from Washington to Denver apparently tried to set shoe on fire, officials said.

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-- Kyrgyzstan ex-foreign minister says deadly protests drove president from office and that she leads interim government.

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-- UConn defeats Stanford 53-47 for NCAA women's title and 78th straight win

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>+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=

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-- 7.8-magnitude earthquake strikes northern Sumatra, Indonesia

>+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=
Watch the all-new "John King, USA" weeknights at 7 ET as John gives
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>+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=+=

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-- 25 miners reported dead in West Virginia mine explosion, CNN reports.

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CNN Breaking News

-- Duke defeats Butler in NCAA basketball championship, 61-59

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CNN Breaking News

-- Dozens of miners are believed trapped after an explosion in a mine in Raleigh County, W.Va., CNN affiliate WCHS reports.

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CNN Breaking News

-- Two employees at U.S. consulate in Peshawar, Pakistan, killed in blast, the U.S. Embassy in Islamabad says.

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CNN Breaking News

-- Space shuttle Discovery blasts off on pre-dawn mission to international space station.

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CNN Breaking News

-- Three explosions go off in rapid succession near the U.S. consulate in the Pakistani city of Peshawar, CNN reports.

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CNN Breaking News

-- 100 miners found alive a week after their coal mine flooded in China, state-run TV reported.

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CNN Breaking News

-- Three separate explosions reported in Baghdad; No word yet on casualties.

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CNN Breaking News

-- Duke defeated West Virginia 78-57 to advance to NCAA title game, where they will face Butler.

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CNN Breaking News

-- Butler reaches NCAA basketball final with 52-50 victory over Michigan State

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CNN Breaking News

-- Employers add 162,000 jobs in March; Jobless rate stays unchanged at 9.7%.

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CNN Breaking News

-- Scott Roeder, an abortion-rights foe convicted of killing a doctor in church, sentenced to at least 50 years in prison.

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-- U.S. sinks pirate skiff and captures mother ship after pirates fire on USS Nicholas in Indian Ocean, Navy says.

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